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X-WR-CALNAME:Plant Proteoform Diversity
X-ORIGINAL-URL:https://snp2prot.uni-halle.de
X-WR-CALDESC:Events for Plant Proteoform Diversity
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DTSTART;TZID=Europe/Berlin:20260512T170000
DTEND;TZID=Europe/Berlin:20260512T170000
DTSTAMP:20260523T204745
CREATED:20260220T105331Z
LAST-MODIFIED:20260512T093218Z
UID:2582-1778605200-1778605200@snp2prot.uni-halle.de
SUMMARY:Colloquium with Johannes Debler (CCDM\, Perth\, Australia)
DESCRIPTION:On 12 May 2026\, Johannes Debler (Centre for Crop and Disease Management\, Perth\, Australia) will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Johannes Debler (CCDM\, Perth\, Australia)\nTitle: Strange New Elements – Silenced genes and rogue DNA in fungal plant pathogens \nDate: Tuesday\, 12 May 2026\nTime: 17:00 pm\nLocation:  Lecture hall E.02 (Heide Süd Campus)   Theodor-Lieser-Strasse 9\, Halle (Saale)  \n\nAbstract: Many plant pathogens survive by staying hidden from their host’s immune system\, but sometimes we can turn that stealth against them. \nWe recently identified a putative avirulence gene silenced by a MULE:MuDR transposon insertion in Ascochyta rabiei\, the causal agent of Ascochyta blight in chickpea. This silencing event may have conferred such a strong evolutionary advantage that it drove a lifestyle shift across the entire species\, reclassifying our understanding of this pathogen. \nBut that’s not all we found hiding. During genome assembly curation\, we stumbled across a mysterious 24 kb circular element carrying an unusual combination of genes. Present in both A. rabiei and A. lentis\, an expanded search has since identified it across 11 fungal plant pathogens separated by millions of years of evolution\, yet remaining strikingly conserved. \nWhat is it? We have no idea\, but it’s definitely not a moon. \n\nIf you like to meet with the speaker\, please contact the host\, Thorsten Langner. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-johannes-debler-ccdm-perth-australia/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260505T123000
DTEND;TZID=Europe/Berlin:20260505T140000
DTSTAMP:20260523T204745
CREATED:20260114T101745Z
LAST-MODIFIED:20260410T093004Z
UID:2408-1777984200-1777989600@snp2prot.uni-halle.de
SUMMARY:Colloquium with Andrea Mattevi (University of Pavia\, Italy)
DESCRIPTION:On 5 May 2026\, Andrea Mattevi (University of Pavia\, Italy) will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Andrea Mattevi (University of Pavia\, Italy)\nTitle: The Enzymology of a Metabolon \nDate: Tuesday\, 5 May 2026\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Coenzyme Q\, CoQ\, is an essential antioxidant ubiquitous in nature. CoQ biosynthesis in humans has thus far been attributed to ten different proteins with many coalescing into a large assembly coined the ‘COQ metabolon’. Metabolons are protein assemblies that channel substrates within a metabolic pathway\, however\, their general aptitude for enzymatic biocatalysis remains poorly understood and several CoQ biosynthetic steps\, including C1-decarboxylation and C1-hydroxylation steps\, remain enigmatic in our understanding. To elucidate the prerequisites for CoQ biosynthesis and moreover\, assess the physicochemical properties of the metabolon\, we sought out to construct the entire metabolon in vitro. We employed an innovative evolution-engineering approach rooted by ancestral sequence reconstruction\, in addition to spectrophotometric and biophysical assays\, and analytical techniques to monitor CoQ biosynthesis. Our findings suggest that metabolons possess heightened catalytic efficiency\, consist of an intricate and dynamic number of protein interactions\, and are overseen by chaperoning and organisational protein mitigators. \nAcknowledgement: ERC project MetaQ \nReferences:\nNicoll\, C.R.\, Alvigini\, L.\, Gottinger\, A. et al. In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis. Nat Catal 7\, 148–160 (2024).\nWang D\, Gottinger A\, et aI. Complete Enzyme Clustering Enhances Coenzyme Q Biosynthesis via Substrate Channeling. bioRxiv [Preprint]. 2025 28:2025.05.24.655883 \n\nIf you like to meet with the speaker\, please contact the host\, Milton T. Stubbs. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-andrea-mattevi-university-of-pavia-italy/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260407T170000
DTEND;TZID=Europe/Berlin:20260407T183000
DTSTAMP:20260523T204745
CREATED:20260129T134249Z
LAST-MODIFIED:20260407T073207Z
UID:2420-1775581200-1775586600@snp2prot.uni-halle.de
SUMMARY:Colloquium with Romy Schmidt-Schippers (Uni Bielefeld\, Germany)
DESCRIPTION:On 7 April 2026\, Romy Schmidt-Schippers (Uni Bielefeld\, Germany) will present insights to her current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Romy Schmidt-Schippers (Uni Bielefeld\, Germany) \nTitle: Dynamic mechanisms controlling transcription factors under hypoxia in plants \nDate: Tuesday\, 7 April 2026\nTime: 17:00 pm\nLocation: Lecture hall E.02 (Heide Süd Campus)   Theodor-Lieser-Strasse 9\, Halle (Saale)  \n\nAbstract: Precise transcriptional reprogramming under hypoxia relies on group VII ETHYLENE RESPONSE FACTORS (ERFVIIs)\, which act as central regulators of low-oxygen gene expression in plants. While oxygen-dependent ERFVII stability regulation is quite well characterized\, molecular mechanisms that modulate their activity after nuclear stabilization are still to be resolved. \nIn our lab\, we identified a repressor protein family in Arabidopsis attenuating the activity of multiple ERFVIIs. Based on protein–protein interaction assays\, transactivation experiments\, and subcellular localization studies\, we show this repressive effect is both redox-sensitive and dependent on defined features within ERFVIIs and repressors\, respectively. Expression profiling and mutant analyses further support a regulatory role for these repressor proteins in balancing transcriptional responses across changing oxygen conditions. Moreover\, redox-related control of repressor abundance appears to contribute to the dynamic responsiveness of this regulatory system under hypoxia. \nOur findings point to a multifaceted post-translational and feedback-driven control mechanism acting on the ERFVII family that complements proteolytic regulation of these transcription factors. Taken together\, this work highlights a crucial\, new regulatory module with relevance for oxygen sensing as well as transcriptional plasticity and plant stress resilience under oxygen constraints. \n\nIf you like to meet with the speaker\, please contact the host\, Lennart Wirthmüller. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-romy-schmidt-schippers-uni-bielefeld-germany/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260127T123000
DTEND;TZID=Europe/Berlin:20260127T140000
DTSTAMP:20260523T204745
CREATED:20250728T144629Z
LAST-MODIFIED:20260109T072555Z
UID:1956-1769517000-1769522400@snp2prot.uni-halle.de
SUMMARY:Colloquium with Pitter Hüsgen (University of Freiburg)
DESCRIPTION:On 27 January 2026\, Pitter Hüsgen (University of Freiburg) will present insights to his current research as part of the SNP2Prot Colloquium Series. \n\nSpeaker: Pitter Hüsgen (University of Freiburg)\nTitle: Single-amino-acid cleavages determine mitochondrial complex integrity \nDate: Tuesday\, 27 January 2026\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: The majority of mitochondrial proteins is nuclear encoded and carry N-terminal presequences as targeting signals that are cleaved by the Mitochondrial Presequence Protease upon import. A subset of these proteins is further processed by the aminopeptidase Intermediate Cleaving Peptidase 55\, which in yeast removes a single N-terminal Phe\, Leu or Tyr residue that otherwise act as degradation signal. The machinery for proteolytic maturation of mitochondrial preproteins is highly conserved and mutations in the human proteins are linked to severe diseases. However\, the reason why specific substrates retain destabilizing N-degrons\, what the molecular consequences are upon loss of Icp55\, and to which degree cleavage events and substrates are conserved in evolution is not known. \nIn my talk I will show that mass spectrometry-based proteome and N-terminome profiling allowed us to identify over one hundred ICP55 substrates in human cells. Most of these are part of protein assemblies that are generally destabilized\, resulting in impaired function. I will further present ongoing comparative N-terminome analysis of Caenorhabditis elegans and Arabidopsis thaliana indicating that at least some substrates are conserved in evolution. Taken together\, our data reveal N-terminal proteoform control as an unexpected\, conserved layer of organellar homeostasis. \n\nIf you like to meet with the speaker\, please contact the host\, Christin Naumann (IPB). \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-pitter-husgen-university-of-freiburg/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260120T170000
DTEND;TZID=Europe/Berlin:20260120T183000
DTSTAMP:20260523T204745
CREATED:20250623T113659Z
LAST-MODIFIED:20251218T140049Z
UID:1817-1768928400-1768933800@snp2prot.uni-halle.de
SUMMARY:Colloquium with Sarah E. O‘Connor (MPI for Chemical Ecology\, Jena)
DESCRIPTION:On 20 January 2026\, Sarah E. O‘Connor (MPI for Chemical Ecology\, Jena) will present insights to her current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Sarah E. O‘Connor (MPI for Chemical Ecology\, Jena) \nTitle: Harnessing the Chemistry of Natural Products \nDate: Tuesday\, 20 January 2026\nTime: 5 pm\nLocation: Lecture hall E.02\, Theodor-Lieser-Strasse 9 (Heide Süd Campus)\, 06120 Halle (Saale) \n\nAbstract: Nature makes thousands of molecules– natural products– that have many applications in medicine and beyond. Plants in particular are an extremely important source of these molecules. Synthetic biology approaches are being used with increasing success to overproduce medicinally and agriculturally important plant-derived molecules in heterologous hosts. However\, to pursue such approaches effectively\, we must first fully understand the chemistry and biology of the biosynthetic pathways that generate these molecules. Given the complexity of plants and plant genomics\, this pathway discovery process has been a major bottleneck in harnessing the chemical power of plants. Our research aims to develop methods and resources to unlock the biosynthesis of complex molecules produced by plants. We are developing new omics methods to find these genes more efficiently. We also explore mechanisms by which these complex plant pathways have evolved to create extraordinary chemical diversity. \n\nIf you like to meet with the speaker\, please contact the host\, Christian Wall or Andrea Sinz. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-sarah-e-oconnor-mpi-for-chemical-ecology-jena/
LOCATION:Jacob-Volhard-Hörsaal 1.01 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20260113T123000
DTEND;TZID=Europe/Berlin:20260113T140000
DTSTAMP:20260523T204745
CREATED:20251215T102737Z
LAST-MODIFIED:20251218T080741Z
UID:2353-1768307400-1768312800@snp2prot.uni-halle.de
SUMMARY:Colloquium with Pablo Manavella (IHSM Malaga\, Spain)
DESCRIPTION:On 13 January 2026\, Pablo Manavella (IHSM Malaga\, Spain) will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Pablo Manavella (IHSM Malaga\, Spain)\nTitle: Tiny Transposons\, Big Effects: How MITEs Organize Chromatin to Shape Gene Expression and Plant Traits – including insights from the role as Editor-in-Chief of The Plant Cell \nDate: Tuesday\, 13 January 2026\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: \n\nIf you like to meet with the speaker\, please contact the host\, Sascha Laubinger. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-pablo-manavella-ihsm-malaga-spain/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251209T131500
DTEND;TZID=Europe/Berlin:20251209T144500
DTSTAMP:20260523T204745
CREATED:20250722T080654Z
LAST-MODIFIED:20251201T104143Z
UID:1932-1765286100-1765291500@snp2prot.uni-halle.de
SUMMARY:Colloquium with Markus Geisler (University of Fribourg\, CH)
DESCRIPTION:On 9 December 2025\, Markus Geisler (University of Fribourg\, CH) will present insights to his current research as part of the SNP2Prot Colloquium Series. \n\nSpeaker: Markus Geisler (University of Fribourg\, CH)\nTitle: Substrate specificity and evolution of plant hormone transporters \nDate: Tuesday\, 9 December 2025\nTime: 13:15 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: In plants\, members of the B-subfamily of ABC (ATP-Binding Cassette) transporters (ABCBs) were shown to own an extraordinarily high substrate specificity for a few auxinic compounds. However\, recently\, several reports have challenged our current view on the reported high substrate specificity of plant ABCBs. \nIn my talk\, I will present recent examples from my lab that are pointing to the concept that a single plant ABCB transporter can transport multiple\, diverse substrates in vivo. For such an event\, I suggest using the term “substrate multi-specificity” in contrast to what had been described for yeast and mammalian ABCs involved in multidrug resistance (MDR) phenomena. Putative advantages and regulatory mechanisms of substrate multi-specificity will be outlined. \nFurther\, I will present an overview on the evolution of Auxin-Transporting ABCBs\, so-called ATAs\, and their master regulator\, the FKBP42\, TWISTED DWARF1 (TWD1). Our findings suggest that ATAs are the first auxin transporters but that regulation by FKBPs\, such as TWD1\, came much later in evolution. \n\nIf you like to meet with the speaker\, please contact the host\, Marcel Quint. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-markus-geisler-university-of-fribourg-ch/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Marcel Quint":MAILTO:marcel.quint@landw.uni-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251202T123000
DTEND;TZID=Europe/Berlin:20251202T140000
DTSTAMP:20260523T204745
CREATED:20251117T105920Z
LAST-MODIFIED:20251128T070256Z
UID:2251-1764678600-1764684000@snp2prot.uni-halle.de
SUMMARY:Cancelled:  Colloquium with Fabrice Roux (LIPME\, Toulouse\, France)
DESCRIPTION:THE COLLOQUIUM WILL BE RESCHEDULED! \nOn 2 December 2025\, Fabrice Roux (LIPME\, Toulouse\, France) will present insights to his current research as part of the SNP2Prot Colloquium Series. \n\nSpeaker: Fabrice Roux (LIPME\, Toulouse\, France)\nTitle: Adaptive plant-microbiota-pathobiota interactions: exploring intraspecific and interspecific genetic diversity \nDate: Tuesday\, 2 December 2025\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Understanding the genetic and molecular mechanisms that shape interactions among hosts\, their microbiota\, and associated pathobiota offers promising avenues for developing sustainable\, environmentally friendly strategies to enhance host health and performance. Yet\, the substantial genetic diversity present within both host species and bacterial species has often been overlooked when searching for novel host–microbe mechanisms that benefit the host. In this talk\, I will first describe the diversity and community structure of the bacterial microbiota and pathobiota across 168 natural populations of Arabidopsis thaliana in southwestern France. I will then present findings from two complementary association-genetics approaches (Genome–Environment Analysis and Genome-Wide Association mapping) to identify (i) the genetic factors in A. thaliana associated with in situ microbiota and pathobiota descriptors\, (ii) the genetic factors associated with the response of A. thaliana to inoculation with key members of its microbiota\, and (iii) genomic regions exhibiting signatures of natural selection. Finally\, I will introduce two newly developed collections of bacterial genetic and genomic resources that enable GWA mapping from the bacterial perspective\, thereby uncovering previously unknown microbial genetic mechanisms that might influence host performance. \n\nIf you like to meet with the speaker\, please contact the host\, Sascha Laubinger. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-fabrice-roux-lipme-toulouse-france/
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251125T170000
DTEND;TZID=Europe/Berlin:20251125T183000
DTSTAMP:20260523T204745
CREATED:20250509T090635Z
LAST-MODIFIED:20251124T092856Z
UID:1683-1764090000-1764095400@snp2prot.uni-halle.de
SUMMARY:Cancelled: Colloquium with Eske Willerslev (Director of CAEG at the University of Copenhagen\, DK)
DESCRIPTION:THE COLLOQUIUM WILL BE RESCHEDULED IN 2026! \n  \nOn 25 November we will welcome Eske Willerslev as a speaker at the SNP2Prot Colloquium Series. In Copenhagen\, he leads the Centre of excellence in Ancient Environmental Genomics (CAEG) and the Ancient Environmental Genomics Initiative for Sustainability (AEGIS). He is a professor at both the University of Copenhagen and University of Cambridge. In addition\, he is Excellence Professor at Bremen University\, Germany. \nSpeaker: Eske Willerslev (Director of CAEG at the University of Copenhagen\, DK)\nTitle: The AEGIS project \nDate: Tuesday\, 25 November 2025\nTime: 5 pm\nLocation: Lecture hall E.02\, Theodor-Lieser-Strasse 9 (Heide Süd Campus)\, 06120 Halle (Saale) \n\nAbstract: The Ancient Environmental Genomics Initiative for Sustainability (AEGIS) \nClimate change poses a critical threat to human food security\, and its impacts are forecast by the IPCC to affect agricultural production across much of the globe\, putting a significant proportion of the world’s population at risk of food insecurity\, if not starvation.\nAlthough modern agricultural practices have built cropping systems that maximise yields in today’s climate\, these typically lack genetic and organismal diversity\, require intensive use of chemical fertilisers\, pesticides\, and heavy irrigation\, and have limited resilience to rapid climatic and environmental change. Attempts to meet the coming challenges of food insecurity and ensuring agricultural sustainability are further constrained by the genetically depleted staple crops\, the slow processes of conventional breeding and our poor understanding of organismal interactions and adaptations in both natural and agro-ecosystems. Yet each unique climate cycle\, coupled with human cultivation and plant domestication (starting ~12\,000 years ago)\, produced novel genetic and organismal configurations\, specific for all types of environments\, but not seen since. This has resulted in an almost – infinite number of past species adaptations and ecosystem responses to climate changes in a wide range of natural and human-modified settings. The great majority of the genetic information underpinning these adaptive responses has been lost through evolutionary change. However\, a rich record of those responses survives in the earth over many thousands and millions of years as ancient environmental DNA (eDNA). \nA single gram of sediment contains billions of DNA fragments and other ancient biomolecules\, providing a comprehensive record of the organisms that inhabited the local environment\, including fungi\, bacteria\, viruses\, wild and domesticated plants and animals – even in the complete absence of living organisms or fossil remains. Following analytical developments in eDNA over the last two decades – and concurrent rapid advances in the ability to technically modify crops and their ecosystems – it is in principle feasible to tap into this vast eDNA archive at scale to reliably retrieve genetic and organismal information from the past and use nature’s own solutions to climate change (across time and environments) as a means for improving future food sustainability. \nThis presentation is an introduction to a newly started large-scale project termed Ancient Environmental Genomics Initiative for Sustainability (AEGIS). The vision behind AEGIS is to build a more sustainable and secure food production system while also preserving biodiversity in cropping systems under climate change. To meet its vision\, the 18 institutions behind AEGIS will develop the essential science and methodology to use ancient eDNA – alongside other ancient and modern biomolecule-based approaches – to identify important organismal associations and genetic adaptations in natural and agro-ecosystems that will improve future food security under climate change. \n  \n\nIf you like to meet with the speaker\, please contact the host\, Alain Tissier. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-eske-willerslev-director-of-caeg-at-the-university-of-copenhagen-dk/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Alain Tissier":MAILTO:Alain.Tissier@ipb-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251118T170000
DTEND;TZID=Europe/Berlin:20251118T183000
DTSTAMP:20260523T204745
CREATED:20250911T113557Z
LAST-MODIFIED:20251014T074333Z
UID:2109-1763485200-1763490600@snp2prot.uni-halle.de
SUMMARY:Colloquium with Anne Claire Conibear (TU Wien\, Austria)
DESCRIPTION:On 18 November 2025\, Anne Claire Conibear (TU Wien\, Austria) will present insights to her current research as part of the SNP2Prot Colloquium Series. \n\nSpeaker: Anne Claire Conibear (TU Wien\, Austria)\nTitle: Posttranslational Modifications of Disordered Proteins \nDate: Tuesday\, 18 November 2025\nTime: 5 pm\nLocation: Lecture hall E.02\, Theodor-Lieser-Strasse 9 (Heide Süd Campus)\, 06120 Halle (Saale) \n\nAbstract: The conformational flexibility of intrinsically disordered proteins and protein regions (IDRs)\, and their accessibility to modifying enzymes make IDRs hot-spots for protein regulation by posttranslational modifications (PTMs). Such PTMs increase the complexity of the proteome and can have central roles in regulating protein function\, location\, interactions and degradation. Little is known\, however\, about how PTMs modulate the conformations and interactions of IDRs\, as they typically occupy multiple conformational states\, have promiscuous interactions\, and are often removed or poorly represented in structural biology studies. In this presentation\, I will discuss our work towards understanding how PTMs modulate the conformations and interactions of IDRs. Protein synthesis and semi-synthesis provides access to site-specifically modified variants of IDRs\, such as the HMGN1 and Tau proteins\, and disordered termini of Hsp90 and β-catenin. These protein variants enable us to study the precise effects of PTMs and cross-talk of multiple PTMs on conformational populations using NMR spectroscopy. With these examples\, I aim to show how integrating chemical protein synthesis with structural biology of IDRs allows us to gain new insights into the effects of PTMs on the conformation\, dynamics and regulation of IDRs. \nReferences:\n[1] Conibear\, A. C.\, Nat. Rev. Chem. 4\, 674-695 (2020).\n[2] Niederacher\, G.\, Urwin\, D.; Dijkwel\, Y.\, Tremethick\, D. J.\, Rosengren\, K. J.\, Becker\, C. F. W.\, Conibear\, A. C.\, RSC Chem. Biol. 2\, 537-550 (2021).\n[3] Iebed\, D.\, Gökler\, T.\, van Ingen\, H.\, Conibear\, A. C.\, ChemBioChem\, 25\, e20241023 (2024).\n[4] Gajsek\, O.\, Becker\, C. F. W.\, Conibear\, A. C.\, Chem. Eur. J. e202403676 (2024). \n\nIf you like to meet with the speaker\, please contact the host\, Clara Schoeder (Uni Leipzig). \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-anne-claire-conibear-tu-wien-austria/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251028T123000
DTEND;TZID=Europe/Berlin:20251028T140000
DTSTAMP:20260523T204745
CREATED:20250722T075903Z
LAST-MODIFIED:20251017T131734Z
UID:1930-1761654600-1761660000@snp2prot.uni-halle.de
SUMMARY:Colloquium with Stephanie Hutin (Centre national de la recherche scientifique\, Grenoble FR)
DESCRIPTION:On 28 October 2025\, Stephanie Hutin (Centre national de la recherche scientifique\, LPCV\, Grenoble FR) will present insights to her current research as part of the SNP2Prot Colloquium Series. \n\nSpeaker: Stephanie Hutin (Centre national de la recherche scientifique\, LPCV\, Grenoble FR)\nTitle: Liquid Logic of Temperature Sensing: Phase Separation of the Thermosensor ELF3 \nDate: Tuesday\, 28 October 2025\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Sensitive and finely tuned temperature sensing and response mechanisms are essential for plant growth\, development\, and reproduction. As global temperatures rise and extreme weather events become more frequent\, understanding how plants perceive and respond to heat is increasingly critical for food security. Recent studies\, including our own\, have revealed an emerging paradigm in cellular regulation: biomolecular condensation—the phase separation of proteins and nucleic acids into dynamic\, membraneless compartments that can rapidly respond to environmental cues. Yet\, how these condensates form and how their biophysical properties translate into functional outcomes in vivo remain poorly understood. \nIn this talk\, I will present our work on the temperature-responsive condensation of the developmental regulator EARLY FLOWERING 3 (ELF3)\, a key component of the plant circadian clock and thermoresponsive pathway. We dissect the role of its prion-like domain (PrLD)\, showing that it forms a monodisperse higher-order oligomer in the dilute phase and undergoes temperature-sensitive phase separation. Polyglutamine (polyQ) tracts within the PrLD fine-tune this temperature response but are not essential for condensation. Upon aging\, the condensates transition into a hydrogel-like state with semi-ordered architecture\, as revealed through an integrated suite of structural and biophysical techniques\, including fluorescence and atomic force microscopy\, small-angle scattering\, electron microscopy\, and X-ray diffraction. \nTogether\, these findings reveal a rich structural and dynamic landscape for the ELF3 PrLD and provide an expanded molecular framework for understanding how plants translate temperature cues into developmental responses through biomolecular condensation. \n\n@ECRs: Meet Stephanie Hutin in an exclusive Meet-the-Speaker session directly after her talk in seminar room 200 (Kurt-Mothes-Straße 3). Take the opportunity to talk with her about topics of interest in a pleasant atmosphere enjoying free PIZZA!! \nIf you like to meet with the speaker\, please contact the host\, Marcel Quint. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/colloquium-with-stephanie-hutin-centre-national-de-la-recherche-scientifique-grenoble-fr/
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Marcel Quint":MAILTO:marcel.quint@landw.uni-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20251014T123000
DTEND;TZID=Europe/Berlin:20251014T140000
DTSTAMP:20260523T204745
CREATED:20251006T091505Z
LAST-MODIFIED:20251006T144947Z
UID:2175-1760445000-1760450400@snp2prot.uni-halle.de
SUMMARY:IPB Colloquium with Heribert Hirt (KAUST\, Saudi Arabia)
DESCRIPTION:On 14 October 2025\, Heribert Hirt (KAUST\, Saudi Arabia) will present insights to his current research as part of the IPB seminar series. \n\nSpeaker: Heribert Hirt (KAUST\, Saudi Arabia)\nTitle: Harnessing the power of desert plants for enabling crop resilience and climate mitigation \nDate: Tuesday\, 14 October 2025\nTime: 12:30 pm\nLocation: Kurt Mothes lecture hall of the IPB (Weinberg 3\, Halle) \n\n\nAbstract: Throughout his career\, Heribert and his team have made seminal contributions to understanding signal transduction pathways and the molecular mechanisms that govern plant–microbe interactions. More recently\, his research has shifted toward identifying and harnessing how beneficial microbes support plant growth under increasing environmental challenges. Below are some of his publications. \nhttps://doi.org/10.1111/tpj.70174 \nhttps://doi.org/10.1093/nar/gkad827 \nhttps://www.pnas.org/doi/full/10.1073/pnas.2107417118 \n\nIf you like to meet with the speaker\, please contact the host\, Debora Gasperini. \n\nSee all upcoming SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare\n\n\n 
URL:https://snp2prot.uni-halle.de/event/ipb-colloquium-with-heribert-hirt-kaust-saudi-arabia/
LOCATION:Leibniz Institute of Plant Biochemistry (IPB)\, Weinberg 3\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250513T123000
DTEND;TZID=Europe/Berlin:20250513T140000
DTSTAMP:20260523T204745
CREATED:20250422T114450Z
LAST-MODIFIED:20250430T073909Z
UID:1658-1747139400-1747144800@snp2prot.uni-halle.de
SUMMARY:Colloquium with Jiorgos Kourelis (Imperial College London\, GB)
DESCRIPTION:On 13 May 2025\, Jiorgos Kourelis will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Jiorgos Kourelis (Imperial College London\, GB)\nTitle: Pikobodies: What does it take to bioengineer NLR immune receptor-nanobody fusions \nDate: Tuesday\, 13 May 2025\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Recurrent epidemics caused by plant pathogens pose a significant threat to global food security. While modifying natural components has been successful to retool the plant immune system\, this approach can be rapidly rendered ineffective by the emergence of new pathogen strains. Made-to-order synthetic plant immune receptors\, however\, offer a promising solution for tailored resistance to pathogen genotypes present in the field. Here we define four technical and conceptual advances which enabled successful engineering of NLR immune receptor-nanobody fusions\, termed Pikobodies\, for this purpose. These advances include 1)evolutionary analysis to identify domain boundaries\, 2) structural modelling to predict nanobody integration boundaries\, 3) rapid screening using transient immune and disease assays\, and 4) guided mutagenesis to abolish autoactivity triggered by some nanobody integrations. We show that plant immune receptors can serve as effective scaffolds for nanobodies that bind fluorescent proteins (FPs)\, and that the resulting immune receptor-nanobody fusions trigger immune responses and confer resistance against plant viruses expressing FPs. Since nanobodies can be raised against most molecules\, immune receptor-nanobody fusions have the potential to generate resistance against most plant pathogens and pests delivering effectors inside host cells. \n\nIf you like to meet with the speaker\, please contact the host\, Mariana Schuster. \n\nSee all SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare
URL:https://snp2prot.uni-halle.de/event/colloquium-with-jiorgos-kourelis-imperial-college-london-gb/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250429T123000
DTEND;TZID=Europe/Berlin:20250429T140000
DTSTAMP:20260523T204745
CREATED:20250214T134825Z
LAST-MODIFIED:20250422T090810Z
UID:1380-1745929800-1745935200@snp2prot.uni-halle.de
SUMMARY:Colloquium with Christina Weinberg (MLU\, General Biochemistry)
DESCRIPTION:On 29 April 2025\, Christina Weinberg will present insights to her current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Christina Weinberg (MLU\, General Biochemistry)\nTitle: Unraveling biology using non-coding RNAs \nDate: Tuesday\, 29 April 2025\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Non-coding RNAs (ncRNAs) have emerged as powerful regulators of cellular function\, extending far beyond their once-presumed roles as passive scaffolds or transcriptional noise. Among ncRNAs\, we study ribozymes – catalytic RNAs capable of self-cleavage – and riboswitches\, structured RNAs that sense specific metabolites to regulate gene expression. We aim to characterize their structural and biochemical properties\, unravel their biological roles\, where they are not known\, or leverage these RNAs as tools to manipulate gene regulatory circuits. In this talk\, I show the discovery and validation of new ncRNA classes and I will present our work on establishing an RNA-seq-technique to monitor ribozyme activity in cells that could be used to screen for new catalytic RNAs. Finally\, I will outline potential synergies with SNP2PROT and plant research initiatives at MLU. \n\nDownload PDF \nIf you like to meet with the speaker\, please contact the host\, Marcel Quint or Christina Weinberg directly. \n\nSee all SNP2Prot colloquia listed here: https://snp2prot.uni-halle.de/events/category/colloquium/ \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare
URL:https://snp2prot.uni-halle.de/event/colloquium-with-christina-weinberg-mlu-general-biochemistry/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Marcel Quint":MAILTO:marcel.quint@landw.uni-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250408T170000
DTEND;TZID=Europe/Berlin:20250408T183000
DTSTAMP:20260523T204745
CREATED:20250214T135432Z
LAST-MODIFIED:20250325T090026Z
UID:1388-1744131600-1744137000@snp2prot.uni-halle.de
SUMMARY:Colloquium with Holger Puchta (KIT\, Karlsruhe)
DESCRIPTION:On 8 April 2025\, Holger Puchta (KIT\, Karlsruhe) will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Holger Puchta (KIT\, Karlsruhe)\nTitle: Applying CRISPR/Cas to plants: From gene editing to genome restructuring \nDate: Tuesday\, 8 April 2025\nTime: 5 pm\nLocation: Lecture hall E.02\, Theodor-Lieser-Strasse 9 (Heide Süd Campus)\, 06120 Halle (Saale) \n\nAbstract: Till today programmable nucleases as CRISPR/Cas have been applied to plants mainly on genes for the improvement of traits. However\, breeding also requires the breaking or establishing genetic linkages on the chromosome level. Recent improvements in sequence analysis of crop plants reveal that multi Mb long inversions occur with high frequency between different genotypes\, leading to crossover suppression. We were not only able to demonstrate that inversions up to almost chromosome size can be achieved in Arabidopsis thaliana by application of CRISPR/Cas\, but also meiotic recombination can be redirected this way. Thus\, on one side a recombination dead region could be reactivated after 5000 years and on the other almost a complete chromosome could be excluded from genetic exchange. We also induced inversions of serval Mbs to move pericentric heterochromatic regions into euchromatic chromosome arms. Interestingly\, we could not detect any significant change in chromatin state nor expression patterns in the next generations. Using Cas9\, we were also able to induce heritable translocations in the Mb range between heterologous chromosomes in Arabidopsis. Again\, we found robust conservation of the transcriptome and the epigenome to such changes. This indicates that we should be able to restructure plant genomes on an even more global scale. Some recent results sustaining this hypothesis will be presented. \n\nDownload PDF \nIf you like to meet with the speaker\, please contact the host\, Sascha Laubinger in advance. \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare
URL:https://snp2prot.uni-halle.de/event/colloquium-with-holger-puchta-kit-karlsruhe/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Sascha Laubinger":MAILTO:sascha.laubinger@genetik.uni-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250311T123000
DTEND;TZID=Europe/Berlin:20250311T140000
DTSTAMP:20260523T204745
CREATED:20250214T135802Z
LAST-MODIFIED:20250228T102735Z
UID:1398-1741696200-1741701600@snp2prot.uni-halle.de
SUMMARY:Colloquium with Roman Kouril (Palacky University Olomouc\, Czech Republic)
DESCRIPTION:On 11 March 2025\, Roman Kouril (Palacky University Olomouc\, Dept. of Biophysics) will present insights to his current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Roman Kouril (Palacky University Olomouc\, Dept. of Biophysics)\nTitle: Mimicking the spruce-type photosystem II supercomplex in Arabidopsis thaliana \nDate: Tuesday\, 11 March 2025\nTime: 12:30 pm\nLocation: Lecture hall (GHS) of Biochemistry\, Kurt-Mothes-Straße 3 (Weinberg Campus)\, 06120 Halle (Saale) \n\nAbstract: Photosystem II (PSII) is a photosynthetic pigment-protein supercomplex consisting of a core and variable number of light-harvesting complexes (LHCII). Current knowledge of structure of green plant PSII supercomplexes comes from evolutionary distant representatives of green algae and flowering plants (angiosperms) and it points number of similar but also distinct features reflecting their position in the evolutionary tree. To make this view more complete\, we performed a structural analysis of the PSII supercomplex from Norway spruce\, a representative of gymnosperms\, using single particle cryo electron microscopy. The solved structure of spruce PSII supercomplex at 2.8 Å resolution\, which allowed us its detailed structural-functional comparison with photosystems from other plant species. We identified specific properties of spruce photosystem II that distinguish it from PSII of other land plants. To explore the potential physiological benefits of these unique properties\, we prepared and studied various Arabidopsis thaliana mutants in an attempt to mimic the spruce-type PSII supercomplex. The results of ongoing research are gradually leading us to identify key features that are important for its formation. \n\nDownload PDF \nIf you like to meet with the speaker\, please contact the host\, Panagiotis Kastritis in advance. \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare
URL:https://snp2prot.uni-halle.de/event/colloquium-with-roman-kouril-palacky-university-olomouc-czech-republic/
LOCATION:Lecture hall (GHS) of Biochemistry (Weinberg Campus)\, Kurt-Mothes-Straße 3\, Halle (Saale\, 06120\, Germany
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Panagiotis Kastritis":MAILTO:panagiotis.kastritis@bct.uni-halle.de
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Berlin:20250120T150000
DTEND;TZID=Europe/Berlin:20250120T170000
DTSTAMP:20260523T204745
CREATED:20250214T140104Z
LAST-MODIFIED:20250422T091024Z
UID:1401-1737385200-1737392400@snp2prot.uni-halle.de
SUMMARY:Colloquium with Ute Krämer (Ruhr University Bochum)
DESCRIPTION:On 20 January 2025\, Ute Krämer will present insights to her current research as part of the SNP2Prot Colloquium Series. \nSpeaker: Ute Krämer (Ruhr University Bochum)\nTitle: “The genetic basis of adaptive physiological traits in the extremophile Arabidopsis halleri” \nDate: Monday\, 20 January 2025\nTime: 3:00 pm\nLocation: Lecture hall E.02\, Theodor-Lieser-Strasse 9 (Heide Süd Campus)\, 06120 Halle (Saale) \n\nAbstract: The extremophile metal hyperaccumulator Arabidopsis halleri is a diploid outcrossing stoloniferous perennial among the closest relatives of Arabidopsis thaliana. A. halleri is known for a vast phenotypic range of its leaf ionome\, with leaf Zn concentrations far above critical toxicity thresholds of ordinary plants\, and for its exceptionally broad edaphic range that includes soils containing toxic levels of heavy metals. Our objective is to unravel the genetic and physiological basis of phenotypic divergence both within A. halleri and by comparison to closely related species\, in an ecological context. I will briefly outline earlier insights related to metal homeostasis from cross-species comparative approaches and then sketch some recent further developments of this work. We established a biodiversity resource of ca. 1\,000 accessions of European A. halleri collected in the field\, which are edaphically and ionomically indexed\, that is\, leaf and soil elemental composition at the site of origin are known for each genotype. I will present results from QTL mapping using the F2 progeny of crosses of phenotypically contrasting parents\, and also from environmental association studies. Then I will show how haplotype-phased genome assemblies helped to identify structural variation at candidate loci. A subset of the identified genomic regions are under study towards the identification of causal genes and polymorphisms. Our results provide examples of the genetic architectures\, genomic alterations\, and gene functions underlying naturally selected extreme physiological traits in plants. At least in part\, the exceptionally large phenotypic range of A. halleri may reflect how plants utilize metals in mineral co-option for functions outside the nutritional requirements of the metalloproteome\, which are largely shared among. Our work provides insights into how plants cope with environmental change\, and can inform crop improvement and the development of plant-based technologies such as phytomining and phytoremediation. \n\nDownload PDF \nIf you like to meet with the speaker\, please contact the host\, Steffen Abel in advance. \nThe SNP2Prot Colloquium Series is integrated to the \n\nHalle Plant Science Colloquium (HPSC) – https://www.landw.uni-halle.de/prof/pflanzenernaehrung/hpsc/\nIPB Seminar Series – https://www.ipb-halle.de/forschung/symposien-und-kolloquien/vortraege/ipb-seminare
URL:https://snp2prot.uni-halle.de/event/20-jan-colloquium-with-ute-kramer-ruhr-university-bochum/
LOCATION:Lecture hall E.02 (Heide Süd Campus)\, Theodor-Lieser-Strasse 9\, Halle (Saale)\, 06120
CATEGORIES:SNP2Prot Colloquia
ORGANIZER;CN="Steffen Abel":MAILTO:Steffen.Abel@ipb-halle.de
END:VEVENT
END:VCALENDAR