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The Collaborative Research Centre CRC 1664 is funded by Deutsche Forschungsgemeinschaft (DFG) from Oct 2024 to Jun 2028
Plant Proteoform Diversity

Plant Proteoform Diversity

Bridging the gap from genetic to phenotypic variation

  • RESEARCH
    • Overview
    • Research Programme
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      • Proteins interacting with nucleic acids
        • A02 // Functional proteoform variation in thermomorphogenesis master regulators
        • A01 // Structure-function analysis of NAC transcription factor proteoforms
        • A03 // Mutation-sensitive prediction of transcription factor-DNA interactions in plants
        • A04 // Quantitative cytogenetic characterisation and structural analysis of REC8 proteoforms in plant meiosis
        • A05 // Targeting of function and structure of Arabidopsis dicing complex proteoforms on microRNA biogenesis
        • A06 // A06 – Functional significance of Argonaute 2 (AGO2) proteoforms in the antiviral response in Arabidopsis thaliana
      • Proteins involved in signalling pathways (upstream of transcription)
        • B01 // Natural allelic variation of PI4P 5-kinases modulating plasma membrane processes in plants
        • B02 // Allelic variation in the control of calcium-dependent protein kinase activity and function in plant-environment interactions
        • B03 // Allelic variation of a vacuolar cation channel modulating ion homeostasis and calcium signalling in plants
        • B04 // Impact of allelic variation in jasmonate repressors on proteoform structure, co-receptor assembly and plant performance
        • B05 // Role of plant SRO proteoforms in tolerance to oxidative and salinity stress
      • Proteins with enzymatic functions
        • C01 // Climate-associated functional polymorphisms of terpene synthases in Arabidopsis thaliana
        • C02 // Relevance of natural allelic variation in YUCCA genes for proteoform modulation, local auxin biosynthesis and phenotypic variation in natural Arabidopsis accessions
        • C03 // Impact of natural LPR1 proteoforms on Fe-dependent phosphate sensing
        • C04 // Function of mevalonate kinase proteoforms in the adaptation to specific climates
        • C05 // Impact of natural allelic variation on structure and function of the immune proteases SAP1 and SAP2
      • Genome- and proteome-wide future resources
        • D01 // Modeling, understanding, and predicting >2 million Arabidopsis proteoforms in the post-genomic era
        • D02 // Development of SNPstar 2.0 and computational prediction of putative proteoform candidates with high functional proteoform variation
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2025

Extended – Call for Proposals: CRC Start-up Funding

12 February, 20262 December, 2025 by Julia Grimmer

The CRC provides start-up funding in 2026 and 2027 to support researchers in developing and realizing their independent project ideas. We therefore encourage Postdocs, PhD students who are (associated) members … Read more

Categories 2025, General

SNP2Prot Kick-off: A Promising Start!

30 March, 20264 March, 2025 by Julia Grimmer

On February 25 and 26, 2025, SNP2Prot members gathered at the Leibniz Institute of Plant Biochemistry (IPB) in Halle (Saale) for the kick-off symposium. It was only two days – … Read more

Categories 2025, General

Next Event:

Seminar – Machine Learning in Regulatory Genomics

Date: 13.04.2026 12:00

On 13 April 2026, Dmitry Penzar (AIRI, Russia) will present an overview AI genomic models. Trainer: Dmitry Penzar (AIRI, Russia)  Topic: Machine Learning in Regulatory Genomics Date: Monday, 13 April ... Read more

See all SNP2Prot events here: EVENTS

Latest Publication:

Wu, X., Bellagio, T., Peng, Y., Czech, L., Lin, M., Lang, P., Epstein, R., Abdelaziz, M., Alexander, J., Alonso-Blanco, C., Andersen, H. L., Berbel, M., Bergelson, J., Bossdorf, O., Burghardt, L., Caton-Darby, M., Colautti, R., Delker, C., Dimitrakopoulos, P. G, …, Quint, M., …, Exposito-Alonso, M. (2026). Rapid adaptation and extinction in synchronized outdoor evolution experiments of Arabidopsis. Science (New York, N.Y.), 391(6792), eadz0777. https://doi.org/10.1126/science.adz0777

See all SNP2Prot publications here: PUBLICATIONS

Devising outdoor evolution experiments with multicellular eukaryotes is always a challenge. Check out the Science article below where SNP2Prot captains M. Quint and C. Delker took part! Congrats to authors across the globe👏 doi.org/10.1126/scie... #Evolution #Arabidopsis @carolindelker.bsky.social

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— SNP2Prot (@snp2prot.bsky.social) 29. März 2026 um 09:21
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