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The Collaborative Research Centre CRC 1664 is funded by Deutsche Forschungsgemeinschaft (DFG) from Oct 2024 to Jun 2028
Plant Proteoform Diversity

Plant Proteoform Diversity

Bridging the gap from genetic to phenotypic variation

  • RESEARCH
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      • Proteins interacting with nucleic acids
        • A02 // Functional proteoform variation in thermomorphogenesis master regulators
        • A01 // Structure-function analysis of NAC transcription factor proteoforms
        • A03 // Mutation-sensitive prediction of transcription factor-DNA interactions in plants
        • A04 // Quantitative cytogenetic characterisation and structural analysis of REC8 proteoforms in plant meiosis
        • A05 // Targeting of function and structure of Arabidopsis dicing complex proteoforms on microRNA biogenesis
        • A06 // A06 – Functional significance of Argonaute 2 (AGO2) proteoforms in the antiviral response in Arabidopsis thaliana
      • Proteins involved in signalling pathways (upstream of transcription)
        • B01 // Natural allelic variation of PI4P 5-kinases modulating plasma membrane processes in plants
        • B02 // Allelic variation in the control of calcium-dependent protein kinase activity and function in plant-environment interactions
        • B03 // Allelic variation of a vacuolar cation channel modulating ion homeostasis and calcium signalling in plants
        • B04 // Impact of allelic variation in jasmonate repressors on proteoform structure, co-receptor assembly and plant performance
        • B05 // Role of plant SRO proteoforms in tolerance to oxidative and salinity stress
      • Proteins with enzymatic functions
        • C01 // Climate-associated functional polymorphisms of terpene synthases in Arabidopsis thaliana
        • C02 // Relevance of natural allelic variation in YUCCA genes for proteoform modulation, local auxin biosynthesis and phenotypic variation in natural Arabidopsis accessions
        • C03 // Impact of natural LPR1 proteoforms on Fe-dependent phosphate sensing
        • C04 // Function of mevalonate kinase proteoforms in the adaptation to specific climates
        • C05 // Impact of natural allelic variation on structure and function of the immune proteases SAP1 and SAP2
      • Genome- and proteome-wide future resources
        • D01 // Modeling, understanding, and predicting >2 million Arabidopsis proteoforms in the post-genomic era
        • D02 // Development of SNPstar 2.0 and computational prediction of putative proteoform candidates with high functional proteoform variation
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Next Event:

SNP2Prot – Retreat 09/26

Date: 17.09.2026 08:00

Date: Thursday & Friday, 17 & 18 September 2026 Venue: IPK Gatersleben, Corrensstraße 3, 06466 Seeland, OT Gatersleben Schedule: Download v270707 Register here! On Thursday and Friday, 17 and 18 September ... Read more

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Latest Publication:

Pandey, V., Hause, F., Iacobucci, C., Ihling, C. H., Tueting, C., Kastritis, P. L., Arlt, C., & Sinz, A. (2026). Revisiting the p53:Sirt1 interaction in light of controlling p53 acetylation levels. Communications Chemistry, 9(1). https://doi.org/10.1038/s42004-026-02127-y

See all SNP2Prot publications here: PUBLICATIONS

Excited to share the SNPstar! preprint! 🌿 SNPstar helps researchers explore how natural variation in Arabidopsis thaliana affects protein structure and function by integrating SNP data, AlphaFold3 models, stability predictions, population context, and more. www.biorxiv.org/content/10.6...

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— SNP2Prot (@snp2prot.bsky.social) 19. Juli 2026 um 04:12

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