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The Collaborative Research Centre CRC 1664 is funded by Deutsche Forschungsgemeinschaft (DFG) from Oct 2024 to Jun 2028
Plant Proteoform Diversity

Plant Proteoform Diversity

Bridging the gap from genetic to phenotypic variation

  • RESEARCH
    • Overview
    • Research Programme
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      • Proteins interacting with nucleic acids
        • A01 // Structure-function analysis of NAC transcription factor proteoforms
        • A02 // Functional proteoform variation in thermomorphogenesis master regulators
        • A03 // Mutation-sensitive prediction of transcription factor-DNA interactions in plants
        • A04 // Quantitative cytogenetic characterisation and structural analysis of REC8 proteoforms in plant meiosis
        • A05 // Targeting of function and structure of Arabidopsis dicing complex proteoforms on microRNA biogenesis
        • A06 // A06 – Functional significance of Argonaute 2 (AGO2) proteoforms in the antiviral response in Arabidopsis thaliana
      • Proteins involved in signalling pathways (upstream of transcription)
        • B01 // Natural allelic variation of PI4P 5-kinases modulating plasma membrane processes in plants
        • B02 // Allelic variation in the control of calcium-dependent protein kinase activity and function in plant-environment interactions
        • B03 // Allelic variation of a vacuolar cation channel modulating ion homeostasis and calcium signalling in plants
        • B04 // Impact of allelic variation in jasmonate repressors on proteoform structure, co-receptor assembly and plant performance
        • B05 // Role of plant SRO proteoforms in tolerance to oxidative and salinity stress
      • Proteins with enzymatic functions
        • C01 // Climate-associated functional polymorphisms of terpene synthases in Arabidopsis thaliana
        • C02 // Relevance of natural allelic variation in YUCCA genes for proteoform modulation, local auxin biosynthesis and phenotypic variation in natural Arabidopsis accessions
        • C03 // Impact of natural LPR1 proteoforms on Fe-dependent phosphate sensing
        • C04 // Function of mevalonate kinase proteoforms in the adaptation to specific climates
        • C05 // Impact of natural allelic variation on structure and function of the immune proteases SAP1 and SAP2
      • Genome- and proteome-wide future resources
        • D01 // Modeling, understanding, and predicting >2 million Arabidopsis proteoforms in the post-genomic era
        • D02 // Development of SNPstar 2.0 and computational prediction of putative proteoform candidates with high functional proteoform variation
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News

Tracing the Evolutionary History of the Temperature-Sensing Prion-like Domain in EARLY FLOWERING 3 Highlights the Uniqueness of AtELF3

3 April, 202530 October, 2024 by Julia Grimmer

Zihao Zhu, Jana Trenner, Carolin Delker and Marcel Quint Molecular Biology and Evolution, Volume 41, Issue 10, October 2024, msae205, https://doi.org/10.1093/molbev/msae205 Abstract: Plants have evolved mechanisms to anticipate and adjust … Read more

Categories 2024, News, Publications

Bioeconomy News: “New SFB: Protein biochemistry meets plant research”

23 January, 202519 June, 2024 by Julia Grimmer

17 June 2024 https://biooekonomie.de/en/news/new-sfb-protein-biochemistry-meets-plant-research The German Research Foundation is funding a new Collaborative Research Centre at the University of Halle-Wittenberg. The focus is on mutations in the genetic material of … Read more

Categories News, News and press publications

MLU: “Neuer Sonderforschungsbereich stärkt MLU-Forschung zu Pflanzen und Proteinen”

23 January, 20253 June, 2024 by Julia Grimmer

31 May 2024 Nummer 072/2024: https://pressemitteilungen.pr.uni-halle.de Rund 12,5 Millionen Euro erhält die Martin-Luther-Universität Halle-Wittenberg (MLU) für ihre Protein- und Pflanzenforschung. Die Deutsche Forschungsgemeinschaft (DFG) bewilligt an der MLU den neuen … Read more

Categories News, News and press publications
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Next Event:

Seminar – Introduction to PyMOL

Date: 27.10.2025 12:00

On 27 October 2025, Christian Tüting will present scientific training introducing the molecular visualization system PyMOL. Trainer: Christian Tüting, Postdoc (project D01) Topic: Introduction to PyMOL (https://www.pymol.org/) Date: Monday, 27 ... Read more

See all SNP2Prot events here: EVENTS

Latest Publication:

Scholl, C. R., Grosch, L., Baradei, J., Kastritis, P. L., Schoeder, C. T., & Laubinger, S. (2025). Form follows function – structural interplay between DCL1 and pri-miRNAs. Trends in Plant Science. Advance online publication. https://doi.org/10.1016/j.tplants.2025.07.016

See all SNP2Prot publications here: PUBLICATIONS

🎉 SNP2Prot turns 1! 🎉 From SNPs to proteoforms, we've spent a year decoding plant protein diversity with 70+ scientists across disciplines. Thanks for following along, here’s to more discoveries ahead! 🌱🧬 #SNP2Prot #PlantScience @dfg.de

— SNP2Prot (@snp2prot.bsky.social) 1. Oktober 2025 um 14:43
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