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The Collaborative Research Centre CRC 1664 is funded by Deutsche Forschungsgemeinschaft (DFG) from Oct 2024 to Jun 2028
Plant Proteoform Diversity

Plant Proteoform Diversity

Bridging the gap from genetic to phenotypic variation

  • RESEARCH
    • Overview
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      • Proteins interacting with nucleic acids
        • A02 // Functional proteoform variation in thermomorphogenesis master regulators
        • A01 // Structure-function analysis of NAC transcription factor proteoforms
        • A03 // Mutation-sensitive prediction of transcription factor-DNA interactions in plants
        • A04 // Quantitative cytogenetic characterisation and structural analysis of REC8 proteoforms in plant meiosis
        • A05 // Targeting of function and structure of Arabidopsis dicing complex proteoforms on microRNA biogenesis
        • A06 // A06 – Functional significance of Argonaute 2 (AGO2) proteoforms in the antiviral response in Arabidopsis thaliana
      • Proteins involved in signalling pathways (upstream of transcription)
        • B01 // Natural allelic variation of PI4P 5-kinases modulating plasma membrane processes in plants
        • B02 // Allelic variation in the control of calcium-dependent protein kinase activity and function in plant-environment interactions
        • B03 // Allelic variation of a vacuolar cation channel modulating ion homeostasis and calcium signalling in plants
        • B04 // Impact of allelic variation in jasmonate repressors on proteoform structure, co-receptor assembly and plant performance
        • B05 // Role of plant SRO proteoforms in tolerance to oxidative and salinity stress
      • Proteins with enzymatic functions
        • C01 // Climate-associated functional polymorphisms of terpene synthases in Arabidopsis thaliana
        • C02 // Relevance of natural allelic variation in YUCCA genes for proteoform modulation, local auxin biosynthesis and phenotypic variation in natural Arabidopsis accessions
        • C03 // Impact of natural LPR1 proteoforms on Fe-dependent phosphate sensing
        • C04 // Function of mevalonate kinase proteoforms in the adaptation to specific climates
        • C05 // Impact of natural allelic variation on structure and function of the immune proteases SAP1 and SAP2
      • Genome- and proteome-wide future resources
        • D01 // Modeling, understanding, and predicting >2 million Arabidopsis proteoforms in the post-genomic era
        • D02 // Development of SNPstar 2.0 and computational prediction of putative proteoform candidates with high functional proteoform variation
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2026

Three excellent projects have been awared with the SNP2Prot Start-up funding

31 March, 2026 by Julia Grimmer

The DFG-funded CRC1664 “Plant Proteoform Dicersity -SNP2Prot”, proudly announces the awarding of its start-up funding initiative. This program invited postdoctoral researchers and doctoral candidates to submit their own innovative research … Read more

Categories 2026, General, News

Next Event:

Seminar – Basics in (confocal) microscopy

Date: 18.05.2026 12:00

On 18 May 2026, Bettina Hause will present basics in light microscopy, focusing on confocal microscopy. Trainer: Bettins Hause (IPB Halle) Topic: Basics in (confocal) microscopy Date: Monday, 18 May ... Read more

See all SNP2Prot events here: EVENTS

Lange Nacht der Wissenschaften Halle © MLU

Latest Publication:

Siefke, E., Arlt, C., & Sinz, A. (2026). Native Mass Spectrometry Reveals Binding Modes of the Tumor Suppressor Protein p53 to Different DNA Response Elements. Journal of the American Society for Mass Spectrometry. Advance online publication. https://doi.org/10.1021/jasms.6c00066

See all SNP2Prot publications here: PUBLICATIONS

Oxygen deprivation due to flooding brings many changes in plant physiology. SNP2Prot hosted Dr Romy Schmidt-Schippers from Uni Bielefeld today. Her work demonstrated key proteins and cellular pathways that adapt upon flood induced hypoxia. #Hypoxia #RCD1 #Arabidopsis #O2 #OxygenSensing #Evolution

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— SNP2Prot (@snp2prot.bsky.social) 7. April 2026 um 18:48
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